Is SKIN1004 Madagascar Centella Ampoule Safe During Pregnancy? (Updated 2026 Guide)
Updated September 8, 2026
SKIN1004 Madagascar Centella Ampoule
Skin1004
SKIN1004 Madagascar Centella Ampoule earns an A grade and is a favorable option for ordinary topical use during pregnancy based on its ingredient assessment. No ingredients are flagged for caution or avoidance, but this ingredient based grade does not mean the finished product or every ingredient has been specifically studied in pregnancy.
Go ahead and use it. Nothing to worry about here.
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What Ingredients Are in SKIN1004 Madagascar Centella Ampoule?
SKIN1004 Madagascar Centella Ampoule has 7 ingredients. All 7 ingredients are considered safe for pregnancy.
cellulose gum
SAFE
Cellulose gum is a water soluble thickening and stabilizing agent derived from plant cellulose, commonly used in food and pharmaceutical products. The evidence reviewed concerns mainly food and eye drop exposure, while concentrated oral and animal gut findings do not establish pregnancy harm from ordinary topical use of this ampoule.
glycerin
SAFE
Glycerin is a colorless, odorless, and sweet tasting humectant commonly used in skincare products to attract and retain moisture in the skin. Glycerin is compatible with ordinary topical use during pregnancy, with low exposure expected from skincare application.
water
SAFE
Water is a clear, tasteless, and essential liquid that sustains all known forms of life. Water is not flagged in this topical ampoule, but the reviewed drinking water evidence does not directly assess pregnancy exposure through skincare.
1 2 hexanediol
SAFE
For ordinary topical use of this ampoule during pregnancy, this ingredient is unflagged, but no ingredient specific pregnancy evidence is available in this assessment.
butylene glycol
SAFE
Butylene glycol is a versatile, colorless, and odorless solvent and humectant commonly used in skincare and cosmetic formulations to help retain moisture and improve product texture. This humectant is unflagged for topical use in this ampoule, but its moisturizing role does not establish pregnancy specific safety.
centella asiatica extract
SAFE
Centella asiatica extract is a natural plant extract known for its soothing, healing, and anti aging properties, commonly used in skincare products. Centella extract is unflagged in this topical ampoule, but the assessment does not establish pregnancy specific safety or support oral supplement use.
ethylhexylglycerin
SAFE
Ethylhexylglycerin is a skin conditioning agent and preservative booster commonly used in cosmetics to enhance product stability and provide mild antimicrobial benefits. This preservative booster is unflagged for topical use in this ampoule, but no ingredient specific pregnancy evidence is available in this assessment.
Answering Your Questions
How much SKIN1004 Madagascar Centella Ampoule is safe during pregnancy?
Use a small amount sufficient to spread a thin layer over the skin, following the directions on your bottle. There is no established pregnancy specific amount in this assessment, so do not treat the A grade as permission for unrestricted application.
Can you use SKIN1004 Madagascar Centella Ampoule daily while pregnant?
Follow the frequency on your bottle rather than increasing applications because of the A grade. When introducing it, try a small area first and stop using it if irritation develops.
Why did SKIN1004 Madagascar Centella Ampoule receive an A grade?
Its A grade comes from simple ingredient based scoring, with no listed ingredients flagged for pregnancy caution or avoidance. Some ingredients are unflagged rather than individually reviewed as safe, so the grade is not proof of pregnancy specific testing.
Can I use this ampoule while breastfeeding?
The pregnancy grade does not establish breastfeeding safety, and this assessment does not include product specific lactation evidence. If you use it, keep it off the nipple and any skin your baby could lick; ask your clinician if you need guidance about your circumstances.
What alternatives should I consider during pregnancy?
If you prefer a simpler routine, consider a basic moisturizer or hydrating serum with a clearly listed formula and its own pregnancy ingredient assessment. Glycerin is a moisturizing ingredient compatible with ordinary topical use during pregnancy, but you should still check the whole formula.
Is Centella asiatica safe to use during pregnancy?
Centella asiatica extract is not flagged in this ampoule's assessment, but that is not the same as a pregnancy specific safety review. This product's A grade concerns ordinary topical use and should not be extended to oral Centella supplements or concentrated extracts taken by mouth.
Does SKIN1004 Madagascar Centella Ampoule contain niacinamide?
Niacinamide is not on the ingredient list assessed for this product. Check your bottle's label to make sure you have the same formula.
Are all SKIN1004 or Korean skincare products pregnancy safe?
You cannot apply this ampoule's A grade to an entire brand or to Korean skincare generally. Check the exact product and ingredient list, including other Centella ampoules, because similar names do not establish the same formula or grade.
What Are Pregnancy Safe Alternatives to SKIN1004 Madagascar Centella Ampoule?
Here are some solid alternatives. Everything below has an A or B grade, meaning no flagged ingredients in our database.
| Grade | Product | Brand | Type |
|---|---|---|---|
| A | Skin1004 Madagascar Centella Ampoule | Skin1004 | skin care ampoule |
| A | Skin1004 Madagascar Centella Ampoule 55Ml | Skin1004 | skin care ampoule |
| A | Skin1004 Madagascar Centella Ampoule 30Ml | Skin1004 | skin care ampoule |
| A | Skin1004 Madagascar Centella Ampoule 120Ml | Skin1004 | skin care ampoule |
Are Other Skin1004 Products Safe During Pregnancy?
We looked at 10 other Skin1004 products. 6 are pregnancy safe (A or B grade), while 4 need a closer look.
| Grade | Product | Type |
|---|---|---|
| A | Madagascar Centella Ampoule | skin ampoule |
| B+ | Madagascar Centella Air-Fit Suncream Light Spf30 Pa++++ | sunscreen |
| B+ | Madagascar Centella Hyalu-Cica Moisture Cream | moisturizer |
| B+ | Madagascar Centella Probio Cica Essence Toner | toner |
How Does SKIN1004 Madagascar Centella Ampoule Compare to Other Skin Care Ampoules?
We graded 11 Skin Care Ampoules for pregnancy safety. Here's how they stack up:
SKIN1004 Madagascar Centella Ampoule earns a A grade, placing it among the top of Skin Care Ampoules. About 54% of products in this category get an A or B grade.
How Do We Score Products for Pregnancy Safety?
We analyze each product's ingredients and category to flag known risks and provide cautionary notices for general category safety concerns.
A - Safe
Excellent choice! All ingredients are considered safe during pregnancy.
What to do: Use with confidence.
B - Likely Safe
Pretty much safe with very minimal risk. Some ingredients may have limited pregnancy studies, but no significant safety concerns have been identified.
What to do: Use with confidence.
C - Limit
Contains ingredients with some pregnancy considerations. Research shows these ingredients may have limited safety data, potential for minor hormonal effects, or require caution based on animal studies.
What to do: Use sparingly and consider safer alternatives when available.
D - Caution
Similar to C grade but contains multiple cautionary ingredients. The combination increases overall concern.
What to do: Try to avoid if that makes you feel better. If you've already used it, no need to panic.
F - Avoid
Contains an ingredient Pregnancy Safe recommends avoiding during pregnancy. This may reflect an established risk or a precaution based on limited evidence; check the ingredient guidance and exposure context.
What to do: Do not use during pregnancy. If you've already used it, don't worry - contact your OBGYN if concerned.
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References
- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-182#182.1745
- https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/3773
- https://pubmed.ncbi.nlm.nih.gov/32625652/
- https://pubmed.ncbi.nlm.nih.gov/36514369/
- https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=OJ%3AL_202500666
- https://pubmed.ncbi.nlm.nih.gov/34774538/
- https://pubmed.ncbi.nlm.nih.gov/25731162/
- https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b32ed9e8-d091-4f16-b416-5a62cdfee49a
- https://www.hfpappexternal.fda.gov/scripts/fdcc/index.cfm?id=GLYCERIN&set=FoodSubstances
- https://pubmed.ncbi.nlm.nih.gov/31840548/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7009851/
- https://www.medicinesinpregnancy.org/leaflets-a-z/glycerin-suppositories/
- https://mothertobaby.org/pregnancy-breastfeeding-exposures/cosmetics/
- https://www.acog.org/womens-health/experts-and-stories/ask-acog/how-much-water-should-i-drink-during-pregnancy
- https://www.cdc.gov/healthy-weight-growth/water-healthy-drinks/index.html
- https://www.cdc.gov/heat-health/hcp/clinical-overview/heat-and-pregnant-women.html
- https://www.cdc.gov/drinking-water/about/index.html
- https://www.cdc.gov/yellow-book/hcp/family-travel/pregnant-travelers.html
- https://www.epa.gov/privatewells/protect-your-homes-water
- https://www.fda.gov/consumers/consumer-updates/bottled-water-everywhere-keeping-it-safe
- https://www.nationalacademies.org/read/10925/chapter/6